UJI SIFAT FISIK SEDIAAN HAND SANITIZER MINYAK ATSIRI SERAI WANGI (Cymbopogon nardus L.)
DOI:
https://doi.org/10.51225/jps.v9i2.100Keywords:
Gel, Minyak atsiri serai wangi, KarbopolAbstract
Lemongrass contains essential oil compounds that have antibacterial activity. The use of lemongrass in the form of essential oil can be incorporated into hand sanitizer preparations. Hand sanitizer preparations require a base. One of the bases often used is Carbopol. This study aims to determine the effect of variations in carbopol gelling agents on the physical properties of lemongrass essential oil hand sanitizer preparations. The research method used in this study was a posttest-only experimental design. Lemongrass essential oil was made into a hand sanitizer preparation using carbopol gelling agent with variations in concentration of 0.5%, 0.75%, and 1.0%. The formulated gel was tested for physical properties, including organoleptic testing, homogeneity testing, pH testing, and spread diameter testing. The results were statistically analyzed using one-way ANOVA and LSD tests to determine the effect of variations in gelling agent concentration on the hand sanitizer preparation. The results of the organoleptic and homogeneity tests showed that FI was white in color, had a distinctive lemongrass aroma, and a slightly thick consistency; FII was white in color, had a distinctive lemongrass aroma, and a thick consistency; and FIII was white in color, had a distinctive lemongrass aroma, and a very thick consistency. All three formulas were homogeneous. The pH test results showed that FI (6.34±0.20), FII (5.74±0.10), and FIII (5.07±0.14) had significant differences (sig<0.05). The spread diameter test results showed that FI (6.71±0.14 cm), FII (5.95±0.21 cm), and FIII (5.22±0.09 cm) had significant differences (sig<0.05). This study concludes that the results of the physical properties test of lemongrass essential oil hand sanitizer preparations, including organoleptic, homogeneity, pH, and spread diameter tests, have met the requirements. The pH and spread diameter test results affect the physical properties of lemongrass essential oil hand sanitizer preparations.
References
Afifah, H., & Nurwaini, S. (2019). Uji Aktivitas Antijamur Gel Serbuk Lidah Buaya (Aloe vera L.) Berbasis Carbopol 934 Terhadap Candida albicans dan Trichophyton mentagrophytes. Pharmacon: Jurnal Farmasi Indonesia. 15(2): 42–51.
Alatas, A. dan Anindhita, M.A., 2023. Pengaruh Carbopol 940 Sebagai Gelling Agent Terhadap Karakteristik Fisikokimia Sediaan Masker Gel Peel-Off Ekstrak Kulit Buah Melon Oranye (Cucumis melo L.). BENZENA Pharmaceutical Scientific Journal. 1(2): 56-71.
Ali, Fahmi, Stevani, H., & Rachmawaty, D. (2019). Formulasi dan Stabilitas Sediaan Body Scrub Bedda Lotong Dengan Variasi Konsentrasi Trietanolamin. Media Farmasi. 15(1):1-7.
Anliza, S., Hamtini dan Rachmawati, N., 2022. Efektivitas Ekstrak Etanol Daun Namnam (Cynometra cauliflora L.) Sebagai Antibakteri Pada Formulasi Sediaan Gel Hand Sanitizer. Lumbung Farmasi: Jurnal Ilmu Kefarmasian, 3(2): 148-154.
Aprilianti, N., Hajrah, & Sastyarina, Y. (2020). Optimasi Polivinilalkohol (PVA) Sebagai Basis Sediaan Gel Antijerawat. In Proceeding of Mulawarman Pharmaceuticals Conferences. 11: 17–21.
Ariyani, F., Setiawan, L. E., & Soetardjo, F. E. (2008). Ekstraksi Minyak Atsiri dari Tanaman Sereh dengan Menggunakan Pelarut Metanol, Aseton, dan N-Heksana. Widya Teknik. 7(2): 124–133.
Asngad, A., Aprilia, B., & Nopitasari, N. (2018). Kualitas Gel Pembersih Tangan (Handsanitizer) dari Ekstrak Batang Pisang dengan Penambahan Alkohol, Triklosan dan Gliserin yang Berbeda Dosisnya. In Bioeksperimen: Jurnal Penelitian Biologi. 4(2): 61–70.
Astuti, D. P., Husni, P., & Hartono, K. (2017). Formulasi dan Uji Stabilitas Fisik Sediaan Gel Antiseptik Tangan Minyak Atsiri Bunga Lavender (Lavandula angustifolia Miller). In Farmaka.15(1): 176–184.
Bhalekar, M.R., Madgulkar, A.R., Kadam, G.J., Road, K., Near, R.T.O., 2015. Evaluation of Gelling Agents for Clindamycin. Word Journal Of Pharmacy And Pharmaceutical Sciences. 4(7): 2022–2033.
Chandra, D. (2019). Pengujian Penetrasi In-Vitro Sediaan Gel, Krim, Gel-Krim Ekstrak Biji Kopi (Coffea arabica L.) Sebagai Antiselulit. JIFI (Jurnal Ilmiah Farmasi Imelda. 3(1): 14–21.
Dewi, B., 2023. Perbandingan Aktivitas Anti Bakteri Sabun Padat Transparan Minyak Atsiri Sereh Wangi (Cymbopogon citrates (DC.) Stapf) terhadap Bakteri Staphylococcus aureus dan Escherycia coli. Oceana Biomedicina Journal. 6(1): 17–25.
Falahi, A., Christi, M., & Oktavionita, J. (2022). Pengaruh Variasi Konsentrasi Carbopol 934 sebagai Pengental Terhadap Sifat Fisik Sediaan Sampo Infusa Daun Pandan Wangi (Pandanus amaryllifolius Roxb.). Jurnal Ilmiah Farmasi AKFAR. 5(1): 24–30.
Febrianie, N. L. (2021). Optimisasi Carbopol sebagai Basis Gel pada Gel Antiseptik Berbasis Alkohol. Proceeding of Mulawarman Pharmaceuticals Conferences: 58–63.
Hidayah, H. F. (2023). Optimasi Sediaan dan Stabilitas Fisik Serum Kombucha Daun Teh Hijau (Camellia sinensis). Disertasi. Universitas Islam Sultan Agung: Semarang.
Kurniasih, N. (2016). Formulasi Sediaan Krim Tipe M/A Ekstrak Biji Kedelai (Glycine max L) : Uji Stabilitas Fisik dan Efek pada Kulit. Skripsi. Fakultas Farmasi Universitas Muhammadiyah Surakarta: Surakarta.
Minoza, F. (2011). Pengaruh Karbopol Terhadap Sifat Fisik dan Daya Sebar Antibakteri Gel Anti jerawat Ekstrak Daging Daun Lidah Buaya (Aloe barbadensis, Mill) Terhadap Propionibacterium acnes. Skripsi. Jurusan Farmasi Fakultas Matematika dan Ilmu Pengetahuan Alam. Universitas Islam Indonesia: Yogyakarta.
Murni, & Rustin, L. (2020). Karakteristik Kandungan Minyak Atsiri Tanaman Sereh Wangi (Cymbopogon nardus L.). Jurnal UIN Alauddin Makassar. 6(1): 227–231.
Mursal, I. L. P., Kusumawati, A. H., & Puspasari, D. H. (2019). Pengaruh Variasi Konsentrasi Gelling Agent Karbopol 940 terhadap Sifat Fisik Sediaan Gel Hand Sanitizer Minyak Atsiri Daun Kemangi (Ocimum sanctum L.). Pharma Xplore : Jurnal Sains dan Ilmu Farmasi. 4(1): 268–277.
Nahira, Nopiyanti, V., & Widyasti, J. H. (2024). Formulasi Variasi Konsentrasi Karbopol 940 Gel Ekstrak Biji Alpukat (Persea americana Mill.) Pada Penyembuhan Luka Sayat Terhadap Kelinci (Oryctolagus cuniculus). Cendekia Journal of Pharmacy. 8(1): 62–70.
Badan Standarisasi Nasional. (1995). Standar Nasional Indonesia (SNI) 06-3953-1995. Minyak Serai. Jakarta: Badan Standarisasi Nasional.
Nidha, A. A., Hadi, P., & Farida, H. (2017). Efektivitas Minyak Atsiri Daun Kemangi (Ocimum Basilicum) sebagai Antiseptik untuk Higiene Tangan. Jurnal Kedokteran Diponegoro. 6(2): 253–260.
Nikam, S. (2017). Anti-acne Gel of Isotretinoin: Formulation and Evaluation. Asian Journal of Pharmaceutical and Clinical Research. 10(11): 257–266.
Nurlisani, Sa'adah, K., Maulana, M., Salhah, Harliantika, Y., 2019. Formulasi dan Evaluasi Sediaan Suspensi Ketoprofen Menggunakan Perbandingan Konsentrasi Suspending Agent Xanthan Gum. in Proceeding Of Sari Mulia University Pharmacy National Seminars. 1(1): 67–75.
Rahmawati, D. A., & Setiawan, I. (2019). The Formulation and Physical Stability Test Of Gel Fruit Strawberry Extract (Fragaria x ananassa Duch.). Journal of Nutraceuticals and Herbal Medicin. 2(1): 38–46.
Rawar, E. A. (2024). Pengaruh Komposisi Basis CMC-Na dan Karbopol Terhadap Karakteristik Sediaan Fisik Gel Minyak Atsiri Bunga Cengkeh. Jurnal Mahasiswa Ilmu Farmasi dan Kesehatan. 2(1): 70–79.
Rizkita, A. (2017). Efektivitas Antibakteri Ekstrak Daun Sereh Wangi, Sirih Hijau, dan Jahe Merah Terhadap Pertumbuhan Streptococcus Mutans. Prosiding Semnastek.
Rowe, R., Sheskey, P., & Quinn, M. (2009). Handbook of Pharmaceutical Excipients (5th ed.). Pharmaceutical Press: American Pharmaceutical Association.
Saryanti, D., Nugraheni, D., Astuti, N. S., & Pertiwi, N. I. (2019). Optimasi Karbopol dan HPMC dalam Formulasi Gel Antijerawat Nanopartikel Ekstrak Daun Sirih (Piper betle Linn). Jurnal Ilmiah Manuntung. 5(2): 122–199.
Sayuti, K., & Yenrina. (2015). Antioksidan Alami dan Sintetik. Andalas University Press.
Singh, H., Gupta, V., Rao, M., & Mangal, A. (2011). Evaluation of Essential Oil Composition of Cymbopogon Spp. International Journal of Pharmaceutical Research. 3(1): 40–43.
Suarantika, F., Patricia, V. M., & Rahma, H. (2023). Karakterisasi dan Identifikasi Senyawa Minyak Atsiri pada Sereh Wangi (Cymbopogon nardus (L.) Rendle) dengan Kromatografi Gas-Spektrometri Massa. Jurnal Mandala Pharmacon Indonesia. 9 (2): 514–523).
Sukawaty, Y., Apriliana, A., & Warnida, H. (2017). Formula dan Evaluasi Sediaan Gel Pembersih Tangan Ekstrak Bawang Tiwai (Eleutherine bulbosa (Mill.) Urb). Jurnal Ilmiah Manuntung. 3 (1): 77–82).
Thomas, N. A., Taupik, M., Nurrohwinta, E. D., Ramadani, D. P. P., & Novreini, N. D. (2023). Uji Penyembuhan Luka Bakar Gel Enzim Bromelin Menggunakan Carbopol 940 Secara In Vivo. Journal Syifa Sciences and Clinical Research. 5(2): 232–244.
Uzma, N. S., Budi, S., & Rahmadhani. (2024). Pengaruh Kombinasi Basis Karbopol 940 dan HPMC Terhadap Evaluasi dan Stabilitas Sediaan Spray Gel Ekstrak Daun Sembung (Blumea balsamifera (L.)). Journal of Pharmaceutical Care and Sciences. 4(2): 239–250.
Yusuf, A. L., Nurawaliah, E., & Harun, N. (2017). Uji Efektivitas Gel Ekstrak Etanol Daun Kelor (Moringa oleifera L.) sebagai Antijamur Malassezia furfur. Kartika : Jurnal Ilmiah Farmasi. 5(2): 38–86.
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