KAJIAN LITERATUR: AKTIVITAS ANTIDIABETES MELLITUS TIPE 2 DAUN ALPUKAT (Persea americana Mill.)
DOI:
https://doi.org/10.51225/jps.v10i1.165Kata Kunci:
Avocado leaves, Type 2 diabetes mellitus, Phytochemicals, Persea americana Mill., In vivo, In vitro, In silicoAbstrak
Diabetes mellitus (DM) is a disease characterized by elevated blood glucose levels (hyperglycemia) caused by insulin deficiency and insulin resistance. The use of natural medicinal products has emerged as an attractive alternative approach. One promising natural resource that can be developed as an active ingredient for traditional antidiabetic medicine is avocado leaves, which contain phytochemical compounds with beneficial health effects. Avocado leaves (Persea americana Mill.) have demonstrated potential in managing diabetes through various in vivo, in vitro, and in silico studies. This literature review aims to provide an overview of the effects of avocado leaf extract administration as an antidiabetic agent for type 2 diabetes mellitus. This literature review was conducted through a comprehensive and systematic search using databases including Google Scholar, NCBI, ScienceDirect, PubMed, and BMC. The results of the reviewed articles indicate that avocado leaf extracts exhibit antidiabetic activity against type 2 diabetes mellitus through in vitro, in vivo, and in silico mechanisms.
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Referensi
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